Influenza vaccine has a protective effect against COVID-19 severity through several mechanisms. The vaccine has an effect of long-lasting protective neutralizing antibodies and specific T cell responses, which could cross-react with SARS-COV2. However, this is unusual to happen because of great diversity among influenza viruses. The most common mechanism behind the theory of trivalent flu vaccine reducing COVID complications is a vaccine-induced change in innate immunity/ There are memory cells that are found in the innate immune compartment and tissue-resident stem cells, which can be activated by natural or artificial antigens. These innate immune cells then will further defend the body against multiple pathogens, other than the ones that are not targeted particularly by the flu vaccine. The researchers suggest: “Given the high similarities of SARS-CoV-2 and influenza viruses with respect to viral structure, transmission, and pathogenic mechanisms, it seems plausible that both viruses are detected by similar or identical pattern recognition receptors. Thdeir binding to viral RNA can then trigger suitable inflammatory and antiviral responses.” Similarly, the study also focused to prove that flu vaccination can also enhance recovery after the onset of COVID-19 as there is an increase in rapid clearance of the virus, preventing its spread into the lung areas. Likewise, the intensity of unregulated cytokine storm which are fatally seen in COVID-19, can be reduced by the flu vaccine.
In conclusion, come get your flu shot now! In the temporality absence of a COVID-19 vaccine, flu vaccination has many potential benefits which will help relieve the strain of severe COVID-19 cases. Do not wait and get your flu shot immediately in this coming flu season as it not only will protect you against the influenza vaccine but help alleviate and improve COVID-19 outcomes. If you have any questions please contact us. This content was originally provided by Lukhpreet Kaur PharmD candidate 2021. Information was derived from News Medical.