Ketamine has many mechanisms of action, it is most known for having dissociative anesthetic properties. But, ketamine also has analgesic, anti-inflammatory, and antidepressant action. Ketamine is a revolutionizing antidepressant research. Many researchers think that ketamine is a game changer when treating depression. Treatments for depression can take weeks to months to start working but even small doses of ketamine can relieve depression symptoms in hours or days. Ketamine has many side effects and abuse potential, but ketamine has a rapid antidepressant effect which can benefit severely depressed patients. If you have any questions about compounded ketamine contact us. This content was originally provided by Catherine Bonacasa PharmD candidate 2021.
There has been a significant increase in the number of opioid overdose related deaths starting from the 1990s. Opioids are commonly prescribed to patients who suffer from acute or chronic pain as a result of having surgery or disease. Other uses include treating coughs, diarrhea, and addiction to other opioids. Some of the most common opioids prescribed are codeine, hydrocodone, morphine, oxycodone, hydromorphone, and fentanyl. Although opioids have great pain-relieving effects, they have addictive and euphoric properties that make them easy to abuse by users. As a result, medical use of these drugs are strictly regulated by the Controlled Substances Act.
Opioids function to control pain by binding to opioid receptors in the brain leading to the inhibition of its neurotransmitter release. When it is used for treating pain, patients may develop tolerance meaning they need more and more of it to get the same effect. Therefore, it can lead to addiction and patients may even try to obtain multiple prescriptions from different doctors and even try to get them filled at different pharmacies. If high doses are taken, it may cause respiratory failure or even death. As a result, physicians and pharmacies are now required to consult the I-STOP/PMP (Prescription Monitoring Program) whenever Schedule II, III, or IV controlled substances are prescribed.
Fentanyl is one of the drugs that are starting to become a substitute for street drugs and illicit drugs such as heroin due to its high potency. Fentanyl is about 100 times stronger than morphine and is medically prescribed in patches. It is important to follow the instructions that are given since misuse can cause increased side effects such as chest pain, hallucinations, changes in heartbeat, difficulty breathing or swallowing, etc. The patches should not be exposed to heat since it can cause more of the drug to be released to the body and cause overdose. They should be removed from the skin after 72 hours.
The use of illegal non-medical injection opioids such as heroin carry a high risk of infection from sharing needles. Users are also at an increased risk of developing Hepatitis A, B and C. Because these drugs are not supervised by healthcare professionals, people are more prone to overdosing and will require medical attention. Since there has been an increased rate of deaths in the United States due to opioids, a drug called Naloxone was developed as an antidote for rapid overdose reversal. Naloxone is marketed as a nasal spray called Narcan, as well as an auto-injector called Evzio. Patients who depend on opioids on a daily basis benefit from carrying a dose of Naloxone around since it is a potentially life-saving medication. Any question about opioid replacement, please contact us.
This content was originally created by Cindy Lau Pharm D Candidate 2020
Seasonal allergies, also known as Hay Fever, typically begin in February and last until the beginning of summer. Every year, millions of Americans suffer from seasonal allergies that include symptoms such as; watery and itchy eyes, sneezing, and runny or stuffy nose. These symptoms are a result of an increase in pollen count released by trees, grasses, flowering plants and weeds that irritate the nasal and oral passages.
If severe, it is suggested that you see an allergist as soon as possible in order to receive the proper diagnosis of what you are specifically allergic to and best regimen to treat.
There are some non-pharmacological strategies to reduce and control the symptoms of seasonal allergies. In general, it is advised that windows and doors stay closed to prevent allergens from entering the home as well as maintaining good hygiene by showering and changing clothes daily which is essential to reduce the amount of allergens present. Also, it is advised to avoid certain activities such as mowing the lawn and garden work. Rinsing out the sinus by using nasal irrigation kits such as Neilmed Sinus Rinse can also get rid of the bacteria lingering in the nose, which can cause itchiness and inflammation. Lastly, checking the pollen count in advance by listening to the weather forecast is vital when planning your outdoor activities.
Although there are several over the counter, non-prescription drugs in the pharmaceutical market, healthcare practitioners mostly prefer the use of Flonase, Zyrtec, or Xyzal. These drugs work by binding to the histamine receptors in the body and therefore blocking the ill effects of an allergic reaction. If you are currently taking other medications or have an underlying health illness, speak with your doctor or pharmacist before taking any medications. Please contact us with any questions.
This content was originally provided by Cindy Lau Pharm D Candidate 2020
Pseudoephedrine, also known under the brand name Sudafed, is a common agent found in many OTC products used to relieve nasal congestion caused by colds and allergies.
This drug is a sympathomimetic or stimulant, and is part of the amphetamine drug class. It works by narrowing blood vessels in the nasal and sinus passageway, which causes a reduction in the feeling of congestion and the production of mucus. The chemical structure of Sudafed is closely related to that of Methamphetamine, commonly known as Crystal Meth, which is a Class II controlled substance and generally illegal unless prescribed for medicinal purposes such as ADHD. For this reason, the sale of any product containing Sudafed became highly regulated, requiring a valid ID indicating the person buying it is 18 or older, and a max sale of 3.5g per day or 7.5g per month.
In Sports, Sudafed is currently on the International Olympic Committee’s banned substances list, which has led to many athletes to be reprimanded for its use.
Sudafed is found in many common OTC products as well such as Aleve, Allegra, Claritin, Mucinex, and Zyrtec, etc. which are all combination medications used for specific indications based on their active ingredients. All the combination products contain a “D” at the end of its name indicating that it contains pseudoephedrine. It is available as a regular tablet, 12 hour extended release (ER) tablet, or 24 hour ER tablet, and a solution in various dosages based on the product.
Due to Sudafed’s stimulant effects it may cause side effects such as insomnia, excitability, and dizziness. At overdose, however rare, the drug may cause tachycardia or palpitations. Before dispensing any product containing pseudoephedrine, it is important to ask the patient about their medical history. This medication should be avoided in any patient that has high blood pressure, glaucoma, diabetes, enlarged prostate, or any thyroid or heart disease.
This content was orginally provided by Yash Talati Pharm D Canidate 2020
Precision Pharmacy is excited and eager to announce the launch of our new blog titled "Precision Opinions" which will be a source of information and resources for the pharmaceutical industry.
We intend to provide many informative and timely posts on a regular basis that cover both general and specific topics related to the pharmacy field such as compounding through our sister store B&H Compounding and other specialties we offer.
Our blog will be helpful in expressing who we are, describing our services and abilities, and of course providing our opinions that we believe will be useful to our loyal customer base.
Be sure to add us to your favorites and check back often, as we will be adding new entries often.
Contributors to our "Precision Opinions" include various team members of Precision Pharmacy, Inc., from registered pharmacists to top management and key personnel. We may also have a guest blogger from time to time, so check back often!